Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

Emerging studies have indicated that leucine-rich repeat kinase 2 (LRRK2) is associated with thyroid cancer (TC). The present study investigated the effect of LRRK2 on the cell cycle and apoptosis in TC, and examined the underlying mechanisms in vitro. To screen TC-associated differentially expresse...

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Detaylı Bibliyografya
Yayımlandı:Int J Oncol
Asıl Yazarlar: Jiang, Zheng-Cai, Chen, Xiao-Jun, Zhou, Qi, Gong, Xiao-Hua, Chen, Xiong, Wu, Wen-Jun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2019
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561619/
https://ncbi.nlm.nih.gov/pubmed/31180559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4816
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