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Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK signaling pathway

Emerging studies have indicated that leucine-rich repeat kinase 2 (LRRK2) is associated with thyroid cancer (TC). The present study investigated the effect of LRRK2 on the cell cycle and apoptosis in TC, and examined the underlying mechanisms in vitro. To screen TC-associated differentially expresse...

詳細記述

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書誌詳細
出版年:Int J Oncol
主要な著者: Jiang, Zheng-Cai, Chen, Xiao-Jun, Zhou, Qi, Gong, Xiao-Hua, Chen, Xiong, Wu, Wen-Jun
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561619/
https://ncbi.nlm.nih.gov/pubmed/31180559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4816
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