Matrine Suppresses Reactive Oxygen Species (ROS)-Mediated MKKs/p38-Induced Inflammation in Oxidized Low-Density Lipoprotein (ox-LDL)-Stimulated Macrophages

BACKGROUND: The objective of this study was to study the anti-inflammatory effect and possibly involved molecular mechanisms of matrine on oxidized low-density lipoprotein (ox-LDL)-exposed macrophages. MATERIAL/METHODS: Cultured human macrophages (THP-1 cell line) were exposed to ox-LDL at final con...

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Vydáno v:Med Sci Monit
Hlavní autoři: Zhou, Junli, Ma, Wangxia, Wang, Xincheng, Liu, Hongbo, Miao, Youliang, Wang, Juanli, Du, Peng, Chen, Yani, Zhang, Yong, Liu, Zhongwei
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2019
Témata:
Lab/In Vitro Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561390/
https://ncbi.nlm.nih.gov/pubmed/31156213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.917151
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