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A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor
As 3D culture has become central to investigation of tissue biology, mammary epithelial organoids have emerged as powerful tools for investigation of epithelial cell polarization and carcinogenesis. However, most current protocols start from single cells suspended in Matrigel, which can also restric...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6561274/ https://ncbi.nlm.nih.gov/pubmed/31101720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702372116 |
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