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MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine

The cell envelope of Mycobacterium tuberculosis is notable for the abundance of mycolic acids (MAs), essential to mycobacterial viability, and of other species-specific lipids. The mycobacterial cell envelope is extremely hydrophobic, which contributes to virulence and antibiotic resistance. However...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Su, Chih-Chia, Klenotic, Philip A., Bolla, Jani Reddy, Purdy, Georgiana E., Robinson, Carol V., Yu, Edward W.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561238/
https://ncbi.nlm.nih.gov/pubmed/31113875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901346116
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