Synthesis of polypeptides via bioinspired polymerization of in situ purified N-carboxyanhydrides

Ribozymes synthesize proteins in a highly regulated local environment to minimize side reactions caused by various competing species. In contrast, it is challenging to prepare synthetic polypeptides from the polymerization of N-carboxyanhydrides (NCAs) in the presence of water and impurities, which...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Song, Ziyuan, Fu, Hailin, Wang, Jiang, Hui, Jingshu, Xue, Tianrui, Pacheco, Lazaro A., Yan, Haoyuan, Baumgartner, Ryan, Wang, Zhiyu, Xia, Yingchun, Wang, Xuefang, Yin, Lichen, Chen, Chongyi, Rodríguez-López, Joaquín, Ferguson, Andrew L., Lin, Yao, Cheng, Jianjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Physical Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561217/
https://ncbi.nlm.nih.gov/pubmed/31088971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901442116
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi