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Suppressor screening reveals common kleisin–hinge interaction in condensin and cohesin, but different modes of regulation

Cohesin and condensin play fundamental roles in sister chromatid cohesion and chromosome segregation, respectively. Both consist of heterodimeric structural maintenance of chromosomes (SMC) subunits, which possess a head (containing ATPase) and a hinge, intervened by long coiled coils. Non-SMC subun...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Xu, Xingya, Yanagida, Mitsuhiro
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561158/
https://ncbi.nlm.nih.gov/pubmed/31072933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902699116
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