Analysis of factor V in zebrafish demonstrates minimal levels needed for early hemostasis

In humans, coagulation factor V (FV) deficiency is a rare, clinically heterogeneous bleeding disorder, suggesting that genetic modifiers may contribute to disease expressivity. Zebrafish possess many distinct advantages including high fecundity, optical clarity, external development, and homology wi...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Weyand, Angela C., Grzegorski, Steve J., Rost, Megan S., Lavik, Kari I., Ferguson, Allison C., Menegatti, Marzia, Richter, Catherine E., Asselta, Rosanna, Duga, Stefano, Peyvandi, Flora, Shavit, Jordan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560344/
https://ncbi.nlm.nih.gov/pubmed/31167819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018029066
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