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Sphingosine kinase 2 inhibitor ABC294640 displays anti-epithelial ovarian cancer activities in vitro and in vivo

Background: ABC294640 is a non-lipid competitive inhibitor of SphK2. It exhibited anti-proliferative activities in many human malignancies, including ovarian cancer. However, its potential mechanism of action remains poorly understood. Methods: In this paper, epithelial ovarian cancer (EOC) cell lin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Song, Keqi, Dai, Lan, Long, Xiaoran, Cui, Xiaojuan, Liu, Yixuan, Di, Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560197/
https://ncbi.nlm.nih.gov/pubmed/31239712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S208519
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