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A Double-Strand Break Does Not Promote Neisseria gonorrhoeae Pilin Antigenic Variation
The major subunit of the type IV pilus (T4p) of Neisseria gonorrhoeae undergoes antigenic variation (AV) dependent on a guanine quadruplex (G4) DNA structure located upstream of the pilin gene. Since the presence of G4 DNA induces genome instability in both eukaryotic and prokaryotic chromosomes, we...
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| Udgivet i: | J Bacteriol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6560144/ https://ncbi.nlm.nih.gov/pubmed/30988037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00256-19 |
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