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A Double-Strand Break Does Not Promote Neisseria gonorrhoeae Pilin Antigenic Variation

The major subunit of the type IV pilus (T4p) of Neisseria gonorrhoeae undergoes antigenic variation (AV) dependent on a guanine quadruplex (G4) DNA structure located upstream of the pilin gene. Since the presence of G4 DNA induces genome instability in both eukaryotic and prokaryotic chromosomes, we...

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Foilsithe in:J Bacteriol
Main Authors: Prister, Lauren L., Xu, Jing, Seifert, H Steven
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560144/
https://ncbi.nlm.nih.gov/pubmed/30988037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00256-19
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