Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation

The presence and absence of RNA modifications regulates RNA metabolism by modulating the binding of writer, reader, and eraser proteins. For 5-methylcytosine (m(5)C) however, it is largely unknown how it recruits or repels RNA-binding proteins. Here, we decipher the consequences of m(5)C deposition...

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Publicat a:Nat Commun
Autors principals: Sajini, Abdulrahim A., Choudhury, Nila Roy, Wagner, Rebecca E., Bornelöv, Susanne, Selmi, Tommaso, Spanos, Christos, Dietmann, Sabine, Rappsilber, Juri, Michlewski, Gracjan, Frye, Michaela
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560067/
https://ncbi.nlm.nih.gov/pubmed/31186410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10020-7
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