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Non-neutral evolution of H3.3-encoding genes occurs without alterations in protein sequence
Histone H3.3 is a developmentally essential variant encoded by two independent genes in human (H3F3A and H3F3B). While this two-gene arrangement is evolutionarily conserved, its origins and function remain unknown. Phylogenetics, synteny and gene structure analyses of H3.3 genes from 32 metazoan gen...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6560044/ https://ncbi.nlm.nih.gov/pubmed/31186448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44800-4 |
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