Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

Reactive astrocytes evolve after brain injury, inflammatory and degenerative diseases, whereby they undergo transcriptomic re-programming. In malignant brain tumors, their function and crosstalk to other components of the environment is poorly understood. Here we report a distinct transcriptional ph...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Henrik Heiland, Dieter, Ravi, Vidhya M., Behringer, Simon P., Frenking, Jan Hendrik, Wurm, Julian, Joseph, Kevin, Garrelfs, Nicklas W. C., Strähle, Jakob, Heynckes, Sabrina, Grauvogel, Jürgen, Franco, Pamela, Mader, Irina, Schneider, Matthias, Potthoff, Anna-Laura, Delev, Daniel, Hofmann, Ulrich G., Fung, Christian, Beck, Jürgen, Sankowski, Roman, Prinz, Marco, Schnell, Oliver
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559986/
https://ncbi.nlm.nih.gov/pubmed/31186414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10493-6
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