Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

Reactive astrocytes evolve after brain injury, inflammatory and degenerative diseases, whereby they undergo transcriptomic re-programming. In malignant brain tumors, their function and crosstalk to other components of the environment is poorly understood. Here we report a distinct transcriptional ph...

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Vydáno v:Nat Commun
Hlavní autoři: Henrik Heiland, Dieter, Ravi, Vidhya M., Behringer, Simon P., Frenking, Jan Hendrik, Wurm, Julian, Joseph, Kevin, Garrelfs, Nicklas W. C., Strähle, Jakob, Heynckes, Sabrina, Grauvogel, Jürgen, Franco, Pamela, Mader, Irina, Schneider, Matthias, Potthoff, Anna-Laura, Delev, Daniel, Hofmann, Ulrich G., Fung, Christian, Beck, Jürgen, Sankowski, Roman, Prinz, Marco, Schnell, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559986/
https://ncbi.nlm.nih.gov/pubmed/31186414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10493-6
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