Tumor-associated reactive astrocytes aid the evolution of immunosuppressive environment in glioblastoma

Reactive astrocytes evolve after brain injury, inflammatory and degenerative diseases, whereby they undergo transcriptomic re-programming. In malignant brain tumors, their function and crosstalk to other components of the environment is poorly understood. Here we report a distinct transcriptional ph...

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Publicado no:Nat Commun
Main Authors: Henrik Heiland, Dieter, Ravi, Vidhya M., Behringer, Simon P., Frenking, Jan Hendrik, Wurm, Julian, Joseph, Kevin, Garrelfs, Nicklas W. C., Strähle, Jakob, Heynckes, Sabrina, Grauvogel, Jürgen, Franco, Pamela, Mader, Irina, Schneider, Matthias, Potthoff, Anna-Laura, Delev, Daniel, Hofmann, Ulrich G., Fung, Christian, Beck, Jürgen, Sankowski, Roman, Prinz, Marco, Schnell, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559986/
https://ncbi.nlm.nih.gov/pubmed/31186414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10493-6
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