Modeling the effect of TNF-α upon drug induced toxicity in human, tissue-engineered myobundles.

A number of significant muscle diseases, such as cachexia, sarcopenia, systemic chronic inflammation, along with inflammatory myopathies share TNF-α-dominated inflammation in their pathogenesis. In addition, inflammatory episodes may increase susceptibility to drug toxicity. To assess the effect of...

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Pubblicato in:Ann Biomed Eng
Autori principali: Davis, Brittany N.J., Santoso, Jeffrey W., Walker, Michaela J., Oliver, Catherine E., Cunningham, Michael M., Boehm, Christian A., Dawes, Danielle, Lasater, Samantha L., Huffman, Kim, Kraus, William E., Truskey, George A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559943/
https://ncbi.nlm.nih.gov/pubmed/30963383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-019-02263-8
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