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Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

Existing in vitro models of human skeletal muscle cannot recapitulate the organization and function of native muscle, limiting their use in physiological and pharmacological studies. Here, we demonstrate engineering of electrically and chemically responsive, contractile human muscle tissues (‘myobun...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Madden, Lauran, Juhas, Mark, Kraus, William E, Truskey, George A, Bursac, Nenad
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337710/
https://ncbi.nlm.nih.gov/pubmed/25575180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04885
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