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Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

Existing in vitro models of human skeletal muscle cannot recapitulate the organization and function of native muscle, limiting their use in physiological and pharmacological studies. Here, we demonstrate engineering of electrically and chemically responsive, contractile human muscle tissues (‘myobun...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Madden, Lauran, Juhas, Mark, Kraus, William E, Truskey, George A, Bursac, Nenad
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337710/
https://ncbi.nlm.nih.gov/pubmed/25575180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04885
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