shRNA-WT1 Potentiates Anticancer Effects of Gemcitabine and Cisplatin Against B16F10 Lung Metastases In Vitro and In Vivo

Background/Aim: High expression level of Wilm’s tumor gene (WT1) in several types of tumors appears to confer disruption of apoptosis and resistance to chemotherapeutic drugs, and correlate with poor outcome. The aim of this work was to determine if down-regulation of WT1 expression results in decre...

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Publicado no:In Vivo
Main Authors: ZAPATA-BENAVIDES, PABLO, ARMENDARIZ-THOMPSON, FERNANDA GUADALUPE, ARELLANO-RODRÍGUEZ, MARIELA, FRANCO-MOLINA, MOISÉS ARMIDES, MENDOZA-GAMBOA, EDGAR, SAAVEDRA-ALONSO, SANTIAGO, ZACARIAS-HERNÁNDEZ, JOSÉ LUIS, TREJO-AVILA, LAURA MARÍA, RODRÍGUEZ-PADILLA, CRISTINA
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559916/
https://ncbi.nlm.nih.gov/pubmed/31028197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11539
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