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Kalirin-7 prevents dendritic spine dysgenesis induced by amyloid beta-derived oligomers
Synapse degeneration and dendritic spine dysgenesis are believed to be crucial early steps in Alzheimer’s disease (AD), and correlate with cognitive deficits in AD patients. Soluble amyloid beta (Aβ)-derived oligomers, also termed Aβ-derived diffusible ligands (ADDLs), accumulate in the brain of AD...
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| Publicado no: | Eur J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6559832/ https://ncbi.nlm.nih.gov/pubmed/30565792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.14311 |
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