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In vitro and in vivo phasor analysis of stoichiometry and pharmacokinetics using short-lifetime near-infrared dyes and time-gated imaging

We introduce a simple new approach for time-resolved multiplexed analysis of complex systems using near-infrared (NIR) dyes, applicable to in vitro and in vivo studies. We show that fast and precise in vitro quantification of NIR fluorophores' short (subnanosecond) lifetime and stoichiometry ca...

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Dettagli Bibliografici
Pubblicato in:J Biophotonics
Autori principali: Chen, Sez-Jade, Sinsuebphon, Nattawut, Rudkouskaya, Alena, Barroso, Margarida, Intes, Xavier, Michalet, Xavier
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559731/
https://ncbi.nlm.nih.gov/pubmed/30421551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbio.201800185
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