تحميل...
Examining the effects of the histone methyltransferase inhibitor BIX-01294 on histone modifications and gene expression in both a clinical population and mouse models
Schizophrenia has been consistently characterized by abnormal patterns of gene down-regulation, increased restrictive chromatin assemblies, and reduced transcriptional activity. Histone methyltransferase (HMT) mRNA and H3K9me2 levels are elevated in postmortem brain and peripheral blood cells of per...
محفوظ في:
| الحاوية / القاعدة: | PLoS One |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science
2019
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6559633/ https://ncbi.nlm.nih.gov/pubmed/31185023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216463 |
| الوسوم: |
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