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Glycyrrhizin protects human melanocytes from H(2)O(2)-induced oxidative damage via the Nrf2-dependent induction of HO-1

Oxidative stress serves a critical role in melanocyte death and is considered to be a major cause of vitiligo. The nuclear factor E2-related factor 2 (Nrf2) signaling pathway has an important role in the antioxidative stress mechanisms of melanocytes. Glycyrrhizin (GR) is a derivative of herbal medi...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Med
Autori principali: Mou, Kuanhou, Pan, Wenjie, Han, Dan, Wen, Xin, Cao, Fang, Miao, Yi, Li, Pan
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6559322/
https://ncbi.nlm.nih.gov/pubmed/31115551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4200
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