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HMGB1 deficiency reduces H(2)O(2)‐induced oxidative damage in human melanocytes via the Nrf2 pathway
Oxidative stress leads to melanocyte death and has been implicated in the pathogenesis of vitiligo. The nuclear factor, E2‐related factor 2 (Nrf2), is a critical transcription factor in protecting cells from oxidative damage. High‐mobility group box 1 (HMGB1) is a chromatin‐associated nuclear protei...
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| Pubblicato in: | J Cell Mol Med |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237592/ https://ncbi.nlm.nih.gov/pubmed/30338917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13895 |
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