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HMGB1 deficiency reduces H(2)O(2)‐induced oxidative damage in human melanocytes via the Nrf2 pathway
Oxidative stress leads to melanocyte death and has been implicated in the pathogenesis of vitiligo. The nuclear factor, E2‐related factor 2 (Nrf2), is a critical transcription factor in protecting cells from oxidative damage. High‐mobility group box 1 (HMGB1) is a chromatin‐associated nuclear protei...
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| Publié dans: | J Cell Mol Med |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237592/ https://ncbi.nlm.nih.gov/pubmed/30338917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13895 |
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