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Hypervascularization in mTOR-dependent focal and global cortical malformations displays differential rapamycin-sensitivity

OBJECTIVES: Patients with mTOR-dependent malformations of cortical development (MCDs) associated with seizures display hyperperfusion and increased vessel density of the dysmorphic cortical tissue. Some studies suggested that the vascular defect occurred independently of seizures. Here, we further e...

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Publicado en:Epilepsia
Main Authors: Zhang, Longbo, Huang, Tianxiang, Teaw, Shannon, Bordey, Angélique
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558978/
https://ncbi.nlm.nih.gov/pubmed/31125447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.15969
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