Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development

BACKGROUND: The maturation of the female germ cell, the oocyte, requires the synthesis and storing of all the necessary metabolites to support multiple divisions after fertilization. Oocyte maturation is only possible in the presence of surrounding, diverse, and changing layers of somatic cells. Our...

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Publicado en:BMC Bioinformatics
Main Authors: Peñalver Bernabé, Beatriz, Thiele, Ines, Galdones, Eugene, Siletz, Anaar, Chandrasekaran, Sriram, Woodruff, Teresa K., Broadbelt, Linda J., Shea, Lonnie D.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558917/
https://ncbi.nlm.nih.gov/pubmed/31182013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2825-2
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