PLEK2 promotes gallbladder cancer invasion and metastasis through EGFR/CCL2 pathway

BACKGROUND: Gallbladder cancer (GBC) is an extremely malignant tumor with a high mortality rate. Little is known about its invasion and metastasis mechanism so far. METHODS: To identify the driver genes in GBC metastasis, we performed a mRNA microarray of metastatic GBC and paired non-tumor samples,...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Shen, Hui, He, Min, Lin, Ruirong, Zhan, Ming, Xu, Sunwang, Huang, Xince, Xu, Chu, Chen, Wei, Yao, Yanhua, Mohan, Man, Wang, Jian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558801/
https://ncbi.nlm.nih.gov/pubmed/31182136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1250-8
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