Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis

BACKGROUND: Prostate cancer (PCa) is considered one of the most prevalent malignancy globally, and metastasis is a major cause of death. Apigenin (API) is a dietary flavonoid which exerts an antimetastatic effect in various cancer types. Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan 1...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Chien, Ming-Hsien, Lin, Yung-Wei, Wen, Yu-Ching, Yang, Yi-Chieh, Hsiao, Michael, Chang, Junn-Liang, Huang, Hsiang-Ching, Lee, Wei-Jiunn
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558790/
https://ncbi.nlm.nih.gov/pubmed/31182131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1247-3
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