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Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease
Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimer’s disease (AD), increasing risk and decreasing age of disease onset. Many studies have demonstrated the detrimental effects of apoE4 in varying cellular contexts. However, the underlying mechanisms explaining how apoE4 leads to c...
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| Publicado no: | Mol Neurodegener |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6558779/ https://ncbi.nlm.nih.gov/pubmed/31186040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-019-0324-6 |
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