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Mechanisms regulating zygotic genome activation

Following fertilization, the two specified gametes must unite to create an entirely new organism. The genome is initially transcriptionally quiescent, allowing the zygote to be reprogrammed to a totipotent state. Gradually, the genome is activated through a process known as the maternal-to-zygotic t...

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Bibliografiska uppgifter
I publikationen:Nat Rev Genet
Huvudupphovsmän: Schulz, Katharine N, Harrison, Melissa M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558659/
https://ncbi.nlm.nih.gov/pubmed/30573849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-018-0087-x
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