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Attenuation of Human Respiratory Viruses by Synonymous Genome Recoding
Using computer algorithms and commercial DNA synthesis, one or more ORFs of a microbial pathogen such as a virus can be recoded and deoptimized by several strategies that may involve the introduction of up to thousands of nucleotide (nt) changes without affecting amino acid (aa) coding. The synonymo...
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| Vydáno v: | Front Immunol |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6558635/ https://ncbi.nlm.nih.gov/pubmed/31231383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01250 |
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