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Non-Peptidic Cell-Penetrating Motifs for Mitochondrion-Specific Cargo Delivery
Mitochondrial dysfunction is linked to a variety of human illnesses, but selective delivery of therapeutics into the mitochondrion has been challenging. We report herein a family of amphipathic cell-penetrating motifs (CPMs) consisting of four guanidinium groups and one or two aromatic hydrophobic g...
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| Udgivet i: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6558518/ https://ncbi.nlm.nih.gov/pubmed/30376611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201811940 |
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