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Non-Peptidic Cell-Penetrating Motifs for Mitochondrion-Specific Cargo Delivery

Mitochondrial dysfunction is linked to a variety of human illnesses, but selective delivery of therapeutics into the mitochondrion has been challenging. We report herein a family of amphipathic cell-penetrating motifs (CPMs) consisting of four guanidinium groups and one or two aromatic hydrophobic g...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: George, Appiah Kubi, Qian, Ziqing, Amiar, Souad, Sahni, Ashweta, Stahelin, Robert V., Pei, Dehua
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558518/
https://ncbi.nlm.nih.gov/pubmed/30376611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201811940
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