Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells

Progesterone plays a protective role in preventing inflammation and preterm delivery during pregnancy. However, the mechanism involved is unknown. Microbial product translocation from a permeable mucosa is demonstrated as a driver of inflammation. To study the mechanism of the protective role of pro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Zejun, Bian, Chuanxiu, Luo, Zhenwu, Guille, Constance, Ogunrinde, Elizabeth, Wu, Jiapeng, Zhao, Min, Fitting, Sylvia, Kamen, Diane L., Oates, Jim C., Gilkeson, Gary, Jiang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6558054/
https://ncbi.nlm.nih.gov/pubmed/31182728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44448-0
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