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A link between plasma microbial translocation, microbiome, and autoantibody development in first-degree relatives of systemic lupus erythematosus patients

OBJECTIVE. Systemic lupus erythematosus (SLE) is characterized by antibody production against self-antigens. However, the events underlying autoantibody formation in SLE remains unclear. This study investigated the role of plasma autoantibody levels, microbial translocation, and the microbiome in SL...

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Vydáno v:Arthritis Rheumatol
Hlavní autoři: Ogunrinde, Elizabeth, Zhou, Zejun, Luo, Zhenwu, Alekseyenko, Alexander, Li, Quan-Zhen, Macedo, Danielle, Kamen, Diane L., Oates, Jim C., Gilkeson, Gary S., Jiang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817371/
https://ncbi.nlm.nih.gov/pubmed/31106972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40935
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