Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages

BACKGROUND: Chronic heavy alcohol drinking (CHD) leads to significant organ damage, increased susceptibility to infections, and delayed wound healing. These adverse outcomes are believed to be mediated by alterations in the function of myeloid cells; however, the mechanisms underlying these changes...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Sureshchandra, Suhas, Stull, Cara, Ligh, Brian Jin Kee, Nguyen, Selene Bich, Grant, Kathleen A., Messaoudi, Ilhem
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
Soggetti:
Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557917/
https://ncbi.nlm.nih.gov/pubmed/31005514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.027
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