Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages

BACKGROUND: Chronic heavy alcohol drinking (CHD) leads to significant organ damage, increased susceptibility to infections, and delayed wound healing. These adverse outcomes are believed to be mediated by alterations in the function of myeloid cells; however, the mechanisms underlying these changes...

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Bibliografiske detaljer
Udgivet i:	EBioMedicine
Main Authors:	Sureshchandra, Suhas, Stull, Cara, Ligh, Brian Jin Kee, Nguyen, Selene Bich, Grant, Kathleen A., Messaoudi, Ilhem
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2019
Fag:	Research paper
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6557917/ https://ncbi.nlm.nih.gov/pubmed/31005514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.027
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Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages

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