Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages

BACKGROUND: Chronic heavy alcohol drinking (CHD) leads to significant organ damage, increased susceptibility to infections, and delayed wound healing. These adverse outcomes are believed to be mediated by alterations in the function of myeloid cells; however, the mechanisms underlying these changes...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Sureshchandra, Suhas, Stull, Cara, Ligh, Brian Jin Kee, Nguyen, Selene Bich, Grant, Kathleen A., Messaoudi, Ilhem
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557917/
https://ncbi.nlm.nih.gov/pubmed/31005514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.027
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