Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages

BACKGROUND: Chronic heavy alcohol drinking (CHD) leads to significant organ damage, increased susceptibility to infections, and delayed wound healing. These adverse outcomes are believed to be mediated by alterations in the function of myeloid cells; however, the mechanisms underlying these changes...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Sureshchandra, Suhas, Stull, Cara, Ligh, Brian Jin Kee, Nguyen, Selene Bich, Grant, Kathleen A., Messaoudi, Ilhem
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Research paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557917/
https://ncbi.nlm.nih.gov/pubmed/31005514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.027
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