International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact

BACKGROUND: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiotic resistance and invasiveness, in the context of...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Gladstone, Rebecca A., Lo, Stephanie W., Lees, John A., Croucher, Nicholas J., van Tonder, Andries J., Corander, Jukka, Page, Andrew J., Marttinen, Pekka, Bentley, Leon J., Ochoa, Theresa J., Ho, Pak Leung, du Plessis, Mignon, Cornick, Jennifer E., Kwambana-Adams, Brenda, Benisty, Rachel, Nzenze, Susan A., Madhi, Shabir A., Hawkins, Paulina A., Everett, Dean B., Antonio, Martin, Dagan, Ron, Klugman, Keith P., von Gottberg, Anne, McGee, Lesley, Breiman, Robert F., Bentley, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557916/
https://ncbi.nlm.nih.gov/pubmed/31003929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.021
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