Whole-blood transcriptomic signatures induced during immunization by chloroquine prophylaxis and Plasmodium falciparum sporozoites

A highly effective vaccine that confers sterile protection to malaria is urgently needed. Immunization under chemoprophylaxis with sporozoites (CPS) consistently confers high levels of protection in the Controlled Human Malaria infection (CHMI) model. To provide a broad, unbiased assessment of the c...

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Publicado no:Sci Rep
Main Authors: Tran, Tuan M., Bijker, Else M., Haks, Mariëlle C., Ottenhoff, Tom H. M., Visser, Leo, Schats, Remko, Venepally, Pratap, Lorenzi, Hernan, Crompton, Peter D., Sauerwein, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557840/
https://ncbi.nlm.nih.gov/pubmed/31182757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44924-7
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