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Immune checkpoint molecule herpes virus entry mediator is overexpressed and associated with poor prognosis in human glioblastoma

BACKGROUND: Dysregulation of immune checkpoint molecules leads to immune evasion in human tumours but has become a viable target for tumour therapy. Here, we examined expression of Herpes virus entry mediator (HVEM), an immune checkpoint molecule, in human glioblastoma (GBM) to assess its potential...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Han, Ming-Zhi, Wang, Shuai, Zhao, Wen-Bo, Ni, Shi-Lei, Yang, Ning, Kong, Yang, Huang, Bin, Chen, An-Jing, Li, Xin-Gang, Wang, Jian, Wang, Dong-Hai
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557785/
https://ncbi.nlm.nih.gov/pubmed/30987862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.002
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