Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure

A number of environmental factors from nutrition to toxicants have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. This requires alterations in the germline (sperm or egg) epigenome. Previously, the agricultural fungicide vinclozolin was found...

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Veröffentlicht in:Epigenetics
Hauptverfasser: Skinner, Michael K., Nilsson, Eric, Sadler-Riggleman, Ingrid, Beck, Daniel, Ben Maamar, Millissia, McCarrey, John R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557599/
https://ncbi.nlm.nih.gov/pubmed/31079544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1614417
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