Transgenerational sperm DNA methylation epimutation developmental origins following ancestral vinclozolin exposure

A number of environmental factors from nutrition to toxicants have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. This requires alterations in the germline (sperm or egg) epigenome. Previously, the agricultural fungicide vinclozolin was found...

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Опубликовано в: :Epigenetics
Главные авторы: Skinner, Michael K., Nilsson, Eric, Sadler-Riggleman, Ingrid, Beck, Daniel, Ben Maamar, Millissia, McCarrey, John R.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2019
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557599/
https://ncbi.nlm.nih.gov/pubmed/31079544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1614417
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