Indoleamine-pyrrole 2,3-dioxygenase-1 (IDO-1) mRNA is over-expressed in the duodenal mucosa and is negatively correlated with serum tryptophan concentrations in dogs with protein-losing enteropathy

INTRODUCTION: Dogs with protein-losing enteropathy (PLE) have decreased serum tryptophan concentrations, which may contribute to disease pathogenesis. Indoleamine-pyrrole 2,3-dioxygenase-1 (IDO-1) expression is associated with low serum tryptophan concentrations and is increased in the gastrointesti...

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發表在:PLoS One
Main Authors: Kathrani, Aarti, Lezcano, Victor, Hall, Edward J., Jergens, Albert E., Seo, Yeon-Jung, Mochel, Jonathan P., Atherly, Todd, Allenspach, Karin
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557522/
https://ncbi.nlm.nih.gov/pubmed/31181125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218218
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