L-dopa response pattern in a rat model of mild striatonigral degeneration

BACKGROUND: Unresponsiveness to dopaminergic therapies is a key feature in the diagnosis of multiple system atrophy (MSA) and a major unmet need in the treatment of MSA patients caused by combined striatonigral degeneration (SND). Transgenic, alpha-synuclein animal models do not recapitulate this la...

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Publicat a:PLoS One
Autors principals: Kaindlstorfer, Christine, Stefanova, Nadia, Garcia, Joanna, Krismer, Florian, Döbrössy, Máté, Göbel, Georg, Jellinger, Kurt, Granata, Roberta, Wenning, Gregor Karl
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557500/
https://ncbi.nlm.nih.gov/pubmed/31181111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218130
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