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The Relevance of Iron in the Pathogenesis of Multiple System Atrophy: A Viewpoint

Iron is essential for cellular development and maintenance of multiple physiological processes in the central nervous system. The disturbance of its homeostasis leads to abnormal iron deposition in the brain and causes neurotoxicity via generation of free radicals and oxidative stress. Iron toxicity...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Kaindlstorfer, Christine, Jellinger, Kurt A., Eschlböck, Sabine, Stefanova, Nadia, Weiss, Günter, Wenning, Gregor K.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798525/
https://ncbi.nlm.nih.gov/pubmed/29376857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170601
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