Genetic resistance to DEHP-induced transgenerational endocrine disruption

Di(2-ethylhexyl)phthalate (DEHP) interferes with sex hormones signaling pathways (SHP). C57BL/6J mice prenatally exposed to 300 mg/kg/day DEHP develop a testicular dysgenesis syndrome (TDS) at adulthood, but similarly-exposed FVB/N mice are not affected. Here we aim to understand the reasons behind...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stenz, Ludwig, Rahban, Rita, Prados, Julien, Nef, Serge, Paoloni-Giacobino, Ariane
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557477/
https://ncbi.nlm.nih.gov/pubmed/31181066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208371
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