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The Mechanism of Environmental Endocrine Disruptors (DEHP) Induces Epigenetic Transgenerational Inheritance of Cryptorchidism

Discussion on the role of DEHP in the critical period of gonadal development in pregnant rats (F0), studied the evolution of F1-F4 generation of inter-generational inheritance of cryptorchidism and the alteration of DNA methylation levels in testis. Pregnant SD rats were randomly divided into two gr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chen, Jinjun, Wu, Shengde, Wen, Sheng, Shen, Lianju, Peng, Jinpu, Yan, Chao, Cao, Xining, Zhou, Yue, Long, Chunlan, Lin, Tao, He, Dawei, Hua, Yi, Wei, Guanghui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452760/
https://ncbi.nlm.nih.gov/pubmed/26035430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126403
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