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Synthesis of 5´-Thio-3´-O-Ribonucleoside Phosphoramidites

The chemical synthesis of phosphoramidite derivatives of all four 5´-deoxy-5´-thioribonucleosides is described. These phosphoramidites contained either trityl (A, G, C and U), dimethoxytrityl (A, G) or tert-butyldisulfanyl (G) as the 5´-S protecting group. The application of several of these phospho...

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Publicat a:J Org Chem
Autors principals: Li, Nan-Sheng, Lu, Jun, Piccirilli, Joseph A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557410/
https://ncbi.nlm.nih.gov/pubmed/29049877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b01484
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