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Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53
Subtelomeric transcription and chromatin can have a significant impact on telomere repeat maintenance and chromosome stability. We have previously found that tumor suppressor protein p53 (TP53) can bind to retrotransposon-like elements in a majority of human subtelomeres to regulate TERRA transcript...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6557208/ https://ncbi.nlm.nih.gov/pubmed/31217894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26980 |
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