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Development of anti-HER2-targeted doxorubicin–core-shell chitosan nanoparticles for the treatment of human breast cancer
Purpose: Doxorubicin (DOX) encapsulated O-succinyl chitosan graft Pluronic(®) F127 (OCP) copolymer nanoparticles conjugated with an anti-HER2 monoclonal antibody were developed as targeted drug delivery vehicles for the treatment of HER2-overexpressing breast cancer. Methods: Five percent and 10% (w...
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| Publicado en: | Int J Nanomedicine |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Dove
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6557189/ https://ncbi.nlm.nih.gov/pubmed/31239670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S198552 |
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